diff --git a/cmake/onnxruntime_unittests.cmake b/cmake/onnxruntime_unittests.cmake
index 0e642c5a7e..ac9770d7ce 100644
--- a/cmake/onnxruntime_unittests.cmake
+++ b/cmake/onnxruntime_unittests.cmake
@@ -975,9 +975,9 @@ if (NOT onnxruntime_ENABLE_TRAINING_TORCH_INTEROP)
     endif()
 
     if (MSVC OR ${CMAKE_SYSTEM_NAME} STREQUAL "Linux")
-        file(GLOB QNN_LIB_FILES LIST_DIRECTORIES false "${onnxruntime_QNN_HOME}/lib/${QNN_ARCH_ABI}/*.so" "${onnxruntime_QNN_HOME}/target/${QNN_ARCH_ABI}/lib/*.so" "${onnxruntime_QNN_HOME}/lib/${QNN_ARCH_ABI}/*.dll" "${onnxruntime_QNN_HOME}/target/${QNN_ARCH_ABI}/lib/*.dll")
+        file(GLOB QNN_LIB_FILES LIST_DIRECTORIES false "${onnxruntime_QNN_HOME}/lib/${QNN_ARCH_ABI}/*.so" "${onnxruntime_QNN_HOME}/lib/${QNN_ARCH_ABI}/*.dll")
         if (${QNN_ARCH_ABI} STREQUAL "aarch64-windows-msvc")
-          file(GLOB EXTRA_HTP_LIB LIST_DIRECTORIES false "${onnxruntime_QNN_HOME}/lib/hexagon-v68/unsigned/libQnnHtpV68Skel.so" "${onnxruntime_QNN_HOME}/target/hexagon-v68/lib/unsigned/libQnnHtpV68Skel.so")
+          file(GLOB EXTRA_HTP_LIB LIST_DIRECTORIES false "${onnxruntime_QNN_HOME}/lib/hexagon-v68/unsigned/libQnnHtpV68Skel.so" "${onnxruntime_QNN_HOME}/lib/hexagon-v73/unsigned/libQnnHtpV73Skel.so")
           list(APPEND QNN_LIB_FILES ${EXTRA_HTP_LIB})
         endif()
         message(STATUS "QNN lib files: " ${QNN_LIB_FILES})
diff --git a/onnxruntime/test/providers/qnn/instance_norm_htp_test.cc b/onnxruntime/test/providers/qnn/instance_norm_htp_test.cc
index f662ac1433..a2aa74c876 100644
--- a/onnxruntime/test/providers/qnn/instance_norm_htp_test.cc
+++ b/onnxruntime/test/providers/qnn/instance_norm_htp_test.cc
@@ -85,9 +85,14 @@ static void RunInstanceNormQDQTest(const TestInputDef<float>& input_def,
 // Check that QNN compiles DQ -> InstanceNormalization -> Q as a single unit.
 // Use an input of rank 4.
 TEST_F(QnnHTPBackendTests, InstanceNormU8) {
-  RunInstanceNormQDQTest(TestInputDef<float>({1, 2, 3, 3}, false, -10.0f, 10.0f),
-                         TestInputDef<float>({2}, true, -2.0f, 2.0f),
-                         TestInputDef<float>({2}, true, -3.0f, 3.0f),
+  // fails with QNN 2.15.1 with the following fixed input.
+  std::vector<float> input_data = {3.21289f, -5.9981f, -1.72799f, 6.27263f, 3.36205f, -1.93515f, -5.40113f, 3.75648f, 6.15357f,
+                                   -5.25769f, 2.73637f, -0.901382f, -6.55612f, 1.99497f, -4.79228f, 2.69813f, 8.3064f, 0.0362501f};
+  std::vector<float> scale_data = {-0.148738f, -1.45158f};
+  std::vector<float> bias_data = {-2.2785083772f, 2.3338717017f};
+  RunInstanceNormQDQTest(TestInputDef<float>({1, 2, 3, 3}, false, input_data).OverrideValueRange(-10.0f, 10.0f),
+                         TestInputDef<float>({2}, true, scale_data).OverrideValueRange(-2.0f, 2.0f),
+                         TestInputDef<float>({2}, true, bias_data).OverrideValueRange(-3.0f, 3.0f),
                          {},
                          ExpectedEPNodeAssignment::All);
 }
@@ -116,4 +121,4 @@ TEST_F(QnnHTPBackendTests, InstanceNormU8Rank5) {
 }  // namespace test
 }  // namespace onnxruntime
 
-#endif
\ No newline at end of file
+#endif