diff --git a/cmake/CMakeLists.txt b/cmake/CMakeLists.txt
index b59824069b..6cfae5ca37 100644
--- a/cmake/CMakeLists.txt
+++ b/cmake/CMakeLists.txt
@@ -791,7 +791,7 @@ function(onnxruntime_set_compile_flags target_name)
     endif()
     if (MSVC)
       foreach(CMAKE_CUDA_TOOLKIT_INCLUDE_DIRECTORY ${CMAKE_CUDA_TOOLKIT_INCLUDE_DIRECTORIES})
-        target_compile_options(${target_name} PRIVATE "$<$<NOT:$<COMPILE_LANGUAGE:CUDA>>:/external:I${CMAKE_CUDA_TOOLKIT_INCLUDE_DIRECTORY}>")
+        target_compile_options(${target_name} PRIVATE "$<$<OR:$<COMPILE_LANGUAGE:C>,$<COMPILE_LANGUAGE:CXX>>:/external:I${CMAKE_CUDA_TOOLKIT_INCLUDE_DIRECTORY}>")
       endforeach()
       foreach(onnxruntime_external_lib IN LISTS onnxruntime_EXTERNAL_LIBRARIES)
         #TODO: the list contains cmake keywords like "debug". We should exclude them.
@@ -802,11 +802,11 @@ function(onnxruntime_set_compile_flags target_name)
               if(onnxruntime_external_lib_include_dir MATCHES "^\\$<BUILD_INTERFACE:([^>]+)>$")
                 string(REGEX REPLACE "^\\$<BUILD_INTERFACE:([^>]+)>$" "\\1" onnxruntime_external_lib_include_dir_cmake "${onnxruntime_external_lib_include_dir}")
                 cmake_path(NATIVE_PATH onnxruntime_external_lib_include_dir_cmake NORMALIZE onnxruntime_external_lib_include_dir_native)
-                target_compile_options(${target_name} PRIVATE "$<$<NOT:$<COMPILE_LANGUAGE:CUDA>>:/external:I${onnxruntime_external_lib_include_dir_native}>")
+                target_compile_options(${target_name} PRIVATE "$<$<OR:$<COMPILE_LANGUAGE:C>,$<COMPILE_LANGUAGE:CXX>>:/external:I${onnxruntime_external_lib_include_dir_native}>")
               endif()
             else()
               cmake_path(NATIVE_PATH onnxruntime_external_lib_include_dir NORMALIZE onnxruntime_external_lib_include_dir_native)
-              target_compile_options(${target_name} PRIVATE "$<$<NOT:$<COMPILE_LANGUAGE:CUDA>>:/external:I${onnxruntime_external_lib_include_dir_native}>")
+              target_compile_options(${target_name} PRIVATE "$<$<OR:$<COMPILE_LANGUAGE:C>,$<COMPILE_LANGUAGE:CXX>>:/external:I${onnxruntime_external_lib_include_dir_native}>")
             endif()
           endforeach()
         endif()
@@ -815,13 +815,13 @@ function(onnxruntime_set_compile_flags target_name)
       if (onnxruntime_ENABLE_MEMLEAK_CHECKER)
         target_compile_definitions(${target_name} PUBLIC -DONNXRUNTIME_ENABLE_MEMLEAK_CHECK)
       endif()
-      target_compile_options(${target_name} PRIVATE "$<$<COMPILE_LANGUAGE:CUDA>:SHELL:--compiler-options /utf-8>" "$<$<NOT:$<COMPILE_LANGUAGE:CUDA>>:/utf-8>")
-      target_compile_options(${target_name} PRIVATE "$<$<COMPILE_LANGUAGE:CUDA>:SHELL:--compiler-options /sdl>" "$<$<NOT:$<COMPILE_LANGUAGE:CUDA>>:/sdl>")
+      target_compile_options(${target_name} PRIVATE "$<$<COMPILE_LANGUAGE:CUDA>:SHELL:--compiler-options /utf-8>" "$<$<OR:$<COMPILE_LANGUAGE:C>,$<COMPILE_LANGUAGE:CXX>>:/utf-8>")
+      target_compile_options(${target_name} PRIVATE "$<$<COMPILE_LANGUAGE:CUDA>:SHELL:--compiler-options /sdl>" "$<$<OR:$<COMPILE_LANGUAGE:C>,$<COMPILE_LANGUAGE:CXX>>:/sdl>")
       set_target_properties(${target_name}
                       PROPERTIES VS_GLOBAL_CAExcludePath "${ORT_BINARY_DIR};${ORT_SOURCE_DIR}")
       if (onnxruntime_ENABLE_STATIC_ANALYSIS)
-        target_compile_options(${target_name} PRIVATE "$<$<COMPILE_LANGUAGE:CUDA>:SHELL:--compiler-options /analyze>" "$<$<NOT:$<COMPILE_LANGUAGE:CUDA>>:/analyze>")
-        target_compile_options(${target_name} PRIVATE "$<$<COMPILE_LANGUAGE:CUDA>:SHELL:--compiler-options /analyze:external->" "$<$<NOT:$<COMPILE_LANGUAGE:CUDA>>:/analyze:external->")
+        target_compile_options(${target_name} PRIVATE "$<$<COMPILE_LANGUAGE:CUDA>:SHELL:--compiler-options /analyze>" "$<$<OR:$<COMPILE_LANGUAGE:C>,$<COMPILE_LANGUAGE:CXX>>:/analyze>")
+        target_compile_options(${target_name} PRIVATE "$<$<COMPILE_LANGUAGE:CUDA>:SHELL:--compiler-options /analyze:external->" "$<$<OR:$<COMPILE_LANGUAGE:C>,$<COMPILE_LANGUAGE:CXX>>:/analyze:external->")
       endif()
     else()
       # Enable warning
diff --git a/cmake/onnxruntime_mlas.cmake b/cmake/onnxruntime_mlas.cmake
index 09a97d880c..85c3501a02 100644
--- a/cmake/onnxruntime_mlas.cmake
+++ b/cmake/onnxruntime_mlas.cmake
@@ -582,9 +582,9 @@ foreach(mlas_target ${ONNXRUNTIME_MLAS_LIBS})
 endforeach()
 set_target_properties(onnxruntime_mlas PROPERTIES FOLDER "ONNXRuntime")
 if (WIN32)
-  target_compile_options(onnxruntime_mlas PRIVATE "/wd6385" "/wd4127")
+  target_compile_options(onnxruntime_mlas PRIVATE "$<$<COMPILE_LANGUAGE:CXX>:/wd6385>" "$<$<COMPILE_LANGUAGE:CXX>:/wd4127>")
   if (onnxruntime_ENABLE_STATIC_ANALYSIS)
-    target_compile_options(onnxruntime_mlas PRIVATE  "/analyze:stacksize 131072")
+    target_compile_options(onnxruntime_mlas PRIVATE  "$<$<COMPILE_LANGUAGE:CXX>:/analyze:stacksize 131072">)
   endif()
 endif()