diff --git a/cmake/CMakeLists.txt b/cmake/CMakeLists.txt
index e1da1eccef..456765a16a 100644
--- a/cmake/CMakeLists.txt
+++ b/cmake/CMakeLists.txt
@@ -1372,6 +1372,14 @@ if (onnxruntime_USE_VITISAI)
 endif()
 
 configure_file(onnxruntime_config.h.in ${CMAKE_CURRENT_BINARY_DIR}/onnxruntime_config.h)
+if(WIN32)
+  configure_file(../requirements.txt.in ${CMAKE_CURRENT_BINARY_DIR}/Debug/requirements.txt)
+  configure_file(../requirements.txt.in ${CMAKE_CURRENT_BINARY_DIR}/Release/requirements.txt)
+  configure_file(../requirements.txt.in ${CMAKE_CURRENT_BINARY_DIR}/RelWithDebInfo/requirements.txt)
+  configure_file(../requirements.txt.in ${CMAKE_CURRENT_BINARY_DIR}/MinSizeRel/requirements.txt)
+else()
+  configure_file(../requirements.txt.in ${CMAKE_CURRENT_BINARY_DIR}/requirements.txt)
+endif()
 
 if (onnxruntime_USE_CUDA)
   #The following 6 lines are copied from https://gitlab.kitware.com/cmake/cmake/issues/17559
diff --git a/requirements.txt b/requirements.txt
deleted file mode 100644
index ebdf9acad1..0000000000
--- a/requirements.txt
+++ /dev/null
@@ -1,3 +0,0 @@
-numpy >= 1.16.6
-protobuf
-flatbuffers
diff --git a/requirements.txt.in b/requirements.txt.in
new file mode 100644
index 0000000000..1040bd79f5
--- /dev/null
+++ b/requirements.txt.in
@@ -0,0 +1,3 @@
+numpy >= @Python_NumPy_VERSION@
+protobuf
+flatbuffers
diff --git a/setup.py b/setup.py
index 8a015ae41a..ae500f6709 100644
--- a/setup.py
+++ b/setup.py
@@ -396,14 +396,6 @@ with open(requirements_path) as f:
     install_requires = f.read().splitlines()
 
 
-if is_manylinux:
-    AUDITWHEEL_PLAT = environ.get('AUDITWHEEL_PLAT', None)
-    if AUDITWHEEL_PLAT == 'manylinux2014_aarch64':
-        for i in range(len(install_requires)):
-            req = install_requires[i]
-            if req.startswith("numpy"):
-                install_requires[i] = "numpy >= 1.19.5"
-
 if enable_training:
     def save_build_and_package_info(package_name, version_number, cuda_version):